Instructor: Michel Bagnat
Summary: We will cover some of the basic cellular processes controlling several key morphogenetic events in metazoans. We will discuss genetic and cell biological approaches for studying morphogenesis and how these are being changed by new biophysical, modeling and physiological models. We will discuss from a cell biological perspective: Meeting 1: symmetry breaking events and early embryonic patterning (AP and DV axis, embryonic layer separation LR asymmetry, etc.); Meeting 2: morphogenetic movements and axis elongation (migration, intercalation, etc.); Meeting 3: morphogenetic movements and organogenesis (epithelial folding, invagination, budding, etc.); and Meeting 4: tubulogenesis; Meetings 5,6: Two sessions of “chalk-talk” presentations of key papers by students.